We are different, but we all do great
Science & we have a lot of fun of doing it!

SOFT CONDENSED MATTER
ROBERT HOŁYST GROUP

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Post-doc from our Team - dr Jeffrey Everts, is among the recipients of the 2022 fellowship for young and outstanding researchers in chemical sciences granted by the Ministry of Education and Science of Poland. Congratulations!
The Cell-IN initiative joins the commercialization projects carried out at the IPC PAS in our Research Group. Cell-IN offers a reagent allowing the introduction of various types of macromolecules (from polymers, proteins, to DNA molecules) into mammalian cells.
Dr. Karol Makuch - post doc from our Team, received SONATA BIS 11 grant from Narodowe Centrum Nauki !!! His project „Diffusion of rigid particles and flexible polymers in complex fluids" received funding of ca. PLN 1.5 MLN. Karol Makuch we are so proud of you, and we wish you a lot of exciting research results!

SOFT CONDENSED MATTER ROBERT HOŁYST GROUP

We are one of the scientific groups from IPC PAS in Warsaw, Poland. Our main goal is to understand and expand knowledge about soft and living matter in vivo and in vitro conditions. We are focus on the transport phenomena in complex liquid, quantitative biophysical chemistry & non-equilibrium processes.

Our Group involves specialists from different science fields, including physicists, biologists, chemists, engineers, and biotechnologists. We are enthusiasts of interdisciplinary projects because we believe that the most interesting things happen in places where two or three fields merge. We are not afraid to think big because the sky is the limit.

The reaction kinetics between like-charged compounds in water is extremely slow due to Coulomb repulsions. Here, we demonstrate that by screening these interactions and, in consequence, increasing the local concentration of reactants, we boost the reactions by many orders of magnitude. The reaction between negatively charged Coenzyme A molecules accelerates ~5 million-fold using cationic micelles. That is ~104 faster kinetics than in 0.5 M NaCl, although the salt is ~106 more concentrated.
Most experimental procedures applied in modern biology involve cargo delivering into cells. One of the ways to cargo introduction is osmotic-mediated intracellular vesicle swelling. However, its widespread use was hindered due to cargo size (<10 nm) and cell-type-related restrictions. We addressed the issue of the composition of colloidal loading solution to enhance the efficiency of cellular delivery.
Biocompatible polyacrylamide gel and core–shell nanoparticles (NPs) were synthesized using a one-step electrochemically initiated gelation. Constant-potential electrochemical decomposing of ammonium persulfate initiated the copolymerization of N-isopropyl acrylamide, methacrylic acid, and N,N′-methylenebisacrylamide monomers.
We study a model of a lipid bilayer membrane described by two order parameters: the chemical composition described using the Gaussian model and the spatial configuration described with the elastic deformation model of a membrane with a finite thickness, or equivalently, for an adherent membrane.
Nitrophenols (NPs) are hazardous pollutants found in various environmental matrices, including ambient fine particulate matter (PM2.5), agricultural residues, rainwater, wildfires, and industrial wastes. This study showed for the first time the effect of three pure nitrophenols and their mixture on human lung cells to provide basic understanding of the NP influence on cell elements and processes.
We investigate the thermal relaxation of an ideal gas from a nonequilibrium stationary state. The gas is enclosed between two walls, which initially have different temperatures. After making one of the walls adiabatic, the system returns to equilibrium.